KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
10.3
Human Site:
Y625
Identified Species:
17.44
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
Y625
L
A
S
L
P
L
G
Y
P
P
H
Q
P
A
Y
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
Y625
L
A
S
L
P
L
G
Y
P
P
H
Q
P
A
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
S361
S
S
S
S
S
S
S
S
S
S
H
F
R
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
F678
P
L
P
P
P
P
G
F
P
P
L
P
P
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
F318
G
A
I
R
L
P
S
F
K
V
K
R
K
E
P
Chicken
Gallus gallus
Q5F3P8
2008
223067
P693
P
P
L
P
P
P
P
P
P
P
P
Q
P
A
F
Frog
Xenopus laevis
Q66J90
1938
216239
V645
C
A
I
T
S
S
S
V
I
P
I
L
P
P
G
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
P673
H
S
T
V
S
H
L
P
S
H
H
P
M
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
S623
D
D
N
M
S
L
S
S
L
S
S
Q
E
D
P
Honey Bee
Apis mellifera
XP_395451
1406
159180
S437
E
D
E
A
L
L
G
S
Y
S
P
A
P
D
E
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
S538
S
S
T
R
R
E
L
S
S
T
H
T
N
S
V
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
L710
P
G
T
M
P
L
V
L
P
S
Q
P
F
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
V111
S
R
Y
S
N
S
N
V
H
N
T
L
A
S
S
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
Y344
L
G
F
A
T
I
R
Y
K
D
S
K
P
T
S
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
13.3
N.A.
33.3
N.A.
N.A.
6.6
40
20
6.6
N.A.
13.3
20
6.6
20
P-Site Similarity:
100
100
N.A.
20
N.A.
40
N.A.
N.A.
20
46.6
20
33.3
N.A.
26.6
20
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
0
15
0
0
0
0
0
0
0
8
8
22
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
0
0
0
0
0
8
0
0
0
15
0
% D
% Glu:
8
0
8
0
0
8
0
0
0
0
0
0
8
8
8
% E
% Phe:
0
0
8
0
0
0
0
15
0
0
0
8
8
0
8
% F
% Gly:
8
15
0
0
0
0
29
0
0
0
0
0
0
8
8
% G
% His:
8
0
0
0
0
8
0
0
8
8
36
0
0
0
8
% H
% Ile:
0
0
15
0
0
8
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
0
8
8
8
0
0
% K
% Leu:
22
8
8
15
15
36
15
8
8
0
8
15
0
8
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
8
0
8
0
0
8
0
0
8
0
0
% N
% Pro:
22
8
8
15
36
22
8
15
36
36
15
22
50
22
29
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
29
0
0
0
% Q
% Arg:
0
8
0
15
8
0
8
0
0
0
0
8
8
0
0
% R
% Ser:
22
22
22
15
29
22
29
29
22
29
15
0
0
15
15
% S
% Thr:
0
0
22
8
8
0
0
0
0
8
8
8
0
8
8
% T
% Val:
0
0
0
8
0
0
8
15
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
22
8
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _